Before joining, Guillermo worked as a Senior Economist at Ecoanalítica, a Venezuelan-based macroeconomic research & consulting firm. There, he served foreign and local private, multilateral, public and social sector organizations providing data, analysis, and advise to understand and navigate the Venezuelan macroeconomy.

He was also a professor of macroeconomics and international finance at Universidad Católica Andrés Bello (Venezuela). Other previous experience include working on economic reform plans with the Venezuelan Opposition and the Government of Kazakhstan. His research interests are focused on industrial policy, innovation, sovereign wealth management, trade shocks, debt, inflation, fiscal policy, sanctions, and political economy.

He holds a Bachelor's degree in Economics from the Universidad Católica Andrés Bello (Venezuela) and a Master in Public Administration and International Development from the Harvard Kennedy School (MPA/ID 2023).